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humans animals metabolism female male genetics pharmacology drug effects physiopathology chemistry adult cytology cattle pathology mice rats blood signal transduction microbiology time factors apoptosis middle aged immunology cells, cultured pregnancy growth & development biosynthesis models, biological etiology antagonists & inhibitors aged veterinary administration & dosage rats, wistar cell line therapeutic use drug therapy enzymology young adult adolescent brain prevention & control psychology Muscle, Skeletal complications ireland gene expression regulation diagnosis mice, inbred c57bl instrumentation molecular sequence data anatomy & histology rna, messenger analysis of variance therapy neurons adverse effects lactation reproducibility of results biomechanics cell line, tumor gene expression bacterial proteins diet mice, knockout cell survival dose-response relationship, drug isolation & purification blood pressure analogs & derivatives rats, sprague-dawley pathogenicity protein binding calcium