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humans female male animals ireland chemistry metabolism adult physiology drug effects education middle aged pharmacology genetics pathology diagnosis aged information retrieval computer science psychology machine translating therapy algorithms therapeutic use drug therapy adolescent prevention & control standards microbiology medicine and health sciences blood physiopathology epidemiology etiology image processing cattle pregnancy sensitivity and specificity administration & dosage educational assessment, evaluation, and research instrumentation surgery reproducibility of results prospective studies risk factors questionnaires time factors treatment outcome mice adverse effects isolation & purification complications this review classification electronic engineering child immunology young adult machine learning aged, 80 and over rats state of the art veterinary digital video cell line irish software engineering statistics & numerical data growth & development real-time organization & administration quality of life large-scale environment multimedia systems