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humans animals metabolism ireland female genetics physiology chemistry male pharmacology drug effects education pathology microbiology adult mice cattle psychology computer science cytology middle aged immunology this review drug therapy physiopathology blood diagnosis therapeutic use irish prevention & control biosynthesis gene expression isolation & purification medicine and health sciences etiology standards aged time factors pregnancy electronic engineering software engineering risk factors apoptosis therapy enzymology epidemiology algorithms biotechnology signal transduction cell line mechanical engineering adverse effects administration & dosage physics veterinary cells, cultured sociology future complications rats models, biological instrumentation cell proliferation classification antagonists & inhibitors economics adolescent management child molecular sequence data environment cell line, tumor geography history