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humans female male animals metabolism physiology ireland genetics adult chemistry middle aged pharmacology drug effects prevention & control psychology aged pathology blood epidemiology physiopathology microbiology adolescent cattle etiology risk factors therapeutic use diagnosis education immunology mice administration & dosage drug therapy time factors therapy pregnancy complications rats adverse effects medicine and health sciences groups young adult child standards case-control studies questionnaires isolation & purification aged, 80 and over veterinary cytology focus groups biosynthesis growth & development gene expression statistics & numerical data surgery classification enzymology prospective studies treatment outcome signal transduction this review irish computer science antagonists & inhibitors instrumentation brain cell line electronic engineering prevalence molecular sequence data physics analogs & derivatives apoptosis gene expression regulation algorithms